The Royal Swedish Academy of Sciences decided to confer the Nobel Prize In Chemistry for the year 2017 to Joachim Frank, Richard Henderson and Jacques Dubochet for their efforts and initiatives for developing the Microscopy of Cyro-Electron for the high-resolution mechanism for the determination of the structures of the Biomolecules in a given solution.
Mr. Dubochet is presently associated with the Lausanne University in Switzerland, while Mr. Frank is serving the Columbia University in the USA. Mr. Henderson is having an association with the MRC Laboratory of Molecular Biology in Cambridge, UK.
Cool microscope Technology- a revolutionary innovation in biochemistry
The innovation of the Nobel-laureate trio simplifies as well as bring improvements in Biomolecules Imaging and this method paves the way for the initiation of a new era in Biochemistry.
Scientific Breakthroughs often arise in the perfect visualization of objects that are normally invisible to the naked eyes. But, Biochemical mapping has been in use for long for filling this blank space.
It is for the reason that the prevailing technologies found it almost impossible to generate an image for the machinery of molecules.
The concept of Cryo-Electron Microscopy will completely change the usual perception and it will allow researchers to freeze the movements of the Biomolecules in the midway and visualize the process that was never seen previously.
This is going to form a decisive observation for Chemistry in the course of daily life as well as for the production of Pharmaceutical products.
A paradigm shift from the conventional perceptions of Electron Microscopy
For a few centuries, it was conceived that the electron Microscopes are suitable to imagine the dead matter. It was for the reason that the strong electron beam usually destroys the Biological matter. However, as Richard Henderson successfully utilized an electron Microscope for producing a 3-dimensional imagining for a Protein at an atomic resolution, it accounted for the potentiality in this technology.
It was Joachim Frank, who made this technology more universal, in terms of its application. In a span of time between the 1970’s and 80’s, he developed a method for processing images that analyzed and revealed a prominent 3-dimensional structure.
Jacques Dubochet holds the credit for adding water to Electron Microscopy. Water evaporates in the vacuum of the Electron Microscope, resulting in the collapse of the Biomolecules. During the initial phase of the 1980’s, he attained success in an experiment to Vitrify Water.
Following the footprints of these innovations, every Nut & Bolt of the Electron Microscope got a complete optimization and now, researchers are in the position to develop 3-dimensional Biomolecule structures, as if a routine function.